Diffuse Pan Bronchiolitis (DPB) is a peculiar airway disease with its pathogenesis enrooted in a complex interplay of various genetic and environmental factors.Airway inflammation, chronic airflow limitation and suppuratives in pulmonary Welding Cable infections are the distinctive features of this entity.It poses a close differential to other freq
FLT3 inhibition upregulates OCT4/NANOG to promote maintenance and TKI resistance of FLT3-ITD+ acute myeloid leukemia
Abstract Up to 30% of acute myeloid leukemia (AML) patients face unfavorable outcomes due to the FMS-like receptor tyrosine kinase-3 (FLT3) internal tandem duplication (ITD) mutation.Although FLT3 inhibitors show encouraging outcomes in treatment, they fail to eliminate leukemia stem cells, the origin of persistent and resistant lesions.Exploration
Why open drug discovery needs four simple rules for licensing data and models.
Scooters When we look at the rapid growth of scientific databases on the Internet in the past decade, we tend to take the accessibility and provenance of the data for granted.As we see a future of increased database integration, the licensing of the data may be a hurdle that hampers progress and usability.We have formulated four rules for licensing